If you were to choose a local trip for four or five days, where would you go?

We are talking about taking a mini vacation.  Not too far away but far enough that it feels like vacation.  There are so many places we have not been that are on the "list".  Savannah, New Orleans, Nashville, the Berkshires, and many more.  Such great locations, I keep hearing.

On our perfect mini-vacation we enjoy food, sites, shows, concerts, beaches and good books.  Wait, add good wine -- at least that's for me.   

Any suggestions for us?